Monday, 1 August 2016
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What is Ezetimibe?
Ezetimibe reduces the amount of cholesterol absorbed by the body.
Ezetimibe is used to treat high cholesterol.
Ezetimibe is sometimes given with other cholesterol-lowering medications.
Important information
Ezetimibe is only part of a complete program of treatment that also includes diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely.
Some cholesterol medications should not be taken at the same time. If you take ezetimibe with another cholesterol medicine, follow your doctor's dosing instructions very carefully.You should not use ezetimibe if you have moderate to severe liver disease. You should not use ezetimibe with a "statin" cholesterol medicine if you have active liver disease, or if you are pregnant or breast-feeding a baby.
Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine.
How should I take ezetimibe?
Ezetimibe may be taken at the same time with fenofibrate, or with a statin medication such as atorvastatin, lovastatin, simvastatin, pravastatin, or fluvastatin.
Some cholesterol medications should not be taken at the same time.
If you also take cholestyramine, colestipol, or colesevelam: You may take ezetimibe 2 hours before taking any of these medicines or wait at least 4 hours after taking any of these other medicines.
You should not take ezetimibe with gemfibrozil.
You may need frequent blood tests to check your liver function if you take ezetimibe with a statin medicine.
It may take up to 2 weeks before your cholesterol levels improve. Keep using your medication as directed. You will need frequent blood tests to measure your cholesterol levels.
Ezetimibe is only part of a complete program of treatment that also includes diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely.
Store at room temperature away from moisture and heat.
Ezetimibe dosing information
- Usual Adult Dose for Hyperlipidemia:
- 10 mg once a day with or without food.
- Usual Adult Dose for Sitosterolemia:
- 10 mg once a day with or without food.
Ezetimibe side effects
Get emergency medical help if you have signs of an allergic reaction to ezetimibe: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Some cholesterol medications can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine.
Side effects may be more likely in older adults.
Common ezetimibe side effects may include:
- muscle or joint pain;
- stuffy nose, sinus pain, sore throat;
- diarrhea; or
- pain in an arm or leg.
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